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"An Introduction to Environmental Epigenetics" to Be Published in September Crowdfunding Campaign Runs Through August 2

合同会社環境エピジェネティクス研究所

Laboratory of Environmental Epigenetics Japan, LEEG will publish *An Introduction to Environmental Epigenetics* (Tokyo Tosho Publishing) in September 2026.

In conjunction with this publication, we are running a project on the crowdfunding site “CAMPFIRE.”


If you support us through crowdfunding (https://camp-fire.jp/projects/907427/view), we will send you a copy of the first edition (with your name listed, if you wish) as they become available, and you will be able to participate free of charge in related online lectures and information exchange sessions.


表紙カバー

Book Cover


Our health and disease are determined not only by our genes themselves but also by environmental factors such as nutritional status from the fetal stage (and, in fact, even earlier—during the lives of our parents, grandparents, and ancestors), exposure to various chemicals and physical conditions, and psychological stress.The mechanism that controls the “switching on and off” of genes is called “epigenetics,” and the field that studies how this mechanism changes due to environmental influences is known as “environmental epigenetics”—a field whose importance is now attracting global attention.Unfortunately, this concept is still not widely known in Japan, so we have begun publishing this book and organizing related activities with the aim of raising awareness among as many people as possible.


環境エピジェネティクス概念図

Conceptual Diagram of Environmental Epigenetics



■Table of Contents (Excerpt)

4 Somatic Cells and Germ Cells

5 Epigenetics

5.1 What Is Epigenetics?

5.2 Mechanisms of Epigenetics

5.3 Germ Cells and Epigenetics

6. Epigenotoxicity

7 Epigenetic Disruptors

7.1 Chemical Substances

8. Transgenerational Health and Disease in Humans and Environmental Epigenetics

8.2 The Environmental Epigenome

8.3 Aging and Epigenetics

9 Environmental Epigenetics and Pollution Caused by Chemical Substances, Food, and Pharmaceuticals in Japan

9.1 Yokkaichi Asthma

9.2 The Morinaga Arsenic Milk Incident

9.3 Itai-itai Disease

9.4 Minamata Disease

9.5 Kanemi Oil Poisoning

September 6: Thalidomide Syndrome

10: Future Toxicity Issues Related to Chemical Substances

10.1 PFAS

10.2 Micro- and Nanoplastics (MNP)

11 Human Diseases and Epigenetics

11.2 Imprinting Disorders

12 Environmental Epigenetics and Evolution



■Book Details

Authors: Toru Shibuya, Koji Horitani

Scheduled Release Date: September 10, 2026

List Price: 2,200 yen (tax included)

Format: A5


Zurich学会でスキナー博士とディスカッション

Discussion with Dr. Skinner at the Zurich Conference



[Company Overview]

Company Name: Environmental Epigenetics Research Institute, LLC

Established: August 2021

Address: 1933-45 Yoshihama, Yugawara-cho, Ashigarashimo-gun, Kanagawa Prefecture

Representative: Toru Shibuya

URL: https://www.leeg.jp/wp/

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