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Human Stem x Needle Water-Light Serum Re/U Spicaine 80" to be launched on February 7 (Wed.)

BYINA株式会社

BYINA Corporation (Head Office: Chuo-ku, Tokyo; Representative: Natsuhi Ueno), which provides various services with human stem cell culture supernatant solution using advanced biotechnology in its own laboratory, will launch a new product "Re/U Spicaine 80" on February 7, 2024 (Wednesday).


New product "Re/U Spicaine 80


Under the concept of "Achieve professional institution-level anti-aging care(*1) at home," Re/U Spicaine 80 is a product formulated with "human stem cell" supernatant(*3) and high-quality natural microneedles = Spicule(*4) to meet the needs for skin problems caused by dryness and aging(*2). Hydrophotonic Needle Serum", which is a combination of "Human Stem Cell Culture Supernatant"(*3) and high-quality natural microneedles = Spicule(*4).

<Spicain" is a cross between "spicule" and "cytokine" contained in stem cell culture supernatant fluid, and this time, "80%" of stem cell culture supernatant fluid is blended. The product name "Spicaine 80" is a combination of "Spicule" and "Cytokine" contained in stem cell culture supernatant fluid.



Three features of the product

1. 80% stem cell culture supernatant liquid, the highest concentration in Re/U's history


Re/U refines raw materials in its own laboratory in Japan.


Re/U contains 80% "stem cell culture supernatant liquid" purified in our own laboratory in Japan. The 2,000 types of cytokines and 20 billion exosomes contained in the raw material approach the concerns of the aging generation. It leads to moisturized and glowing skin. 2.


2. "Premium Tox Needle Powder," a spicule with an ultra-fine needle structure


Spicule adopts "Premium Tox Needle Powder


Premium Tox Needle Powder (ingredient name: Hydrolyzed Kaemen (skin-conditioning ingredient)) is a natural microneedle with an ultra-fine needle structure (hereinafter referred to as "spicule").

The particles of spongia, a sponge animal that lives at the bottom of clean lakes in Europe, are made ultrafine and uniform with a length of approximately 0.2 mm, and impurities are removed.

During product development, repeated trial runs were conducted to find the best concentration of stem cell culture supernatant solution and microneedles, since they are in contact with the skin, and a combination of 80% stem cell culture supernatant solution and 0.1% of spicule concentration was reached.


Image of Spicule and stem cell culture supernatant solution penetrating into stratum corneum


Spicule has numerous cavities, and stem cell culture supernatant solution permeates through these holes. Spicule sends stem cell culture supernatant solution into the stratum corneum, and also maintains a sense of firmness by staying in the stratum corneum. The cocktail of stem cell culture supernatant solution and spicule, a Re/U speciality, will make your skin firm, moist, and hydrated and achieve a glowing skin. 3.


3. delivery by frozen delivery

Cytokines in stem cell culture supernatant solution gradually lose their activity at room temperature (20℃). In order to use the product in a better condition, it is delivered "frozen" like other Re/U products.


*1 Age-appropriate care

*2 Age-appropriate skin concerns

*3 Moisturizing ingredients

*4 Skin-conditioning ingredients



■Product Outline

Product name :Re/U Spicaine 80

Content :5ml

Price : 9,800 yen (tax included)

General release date: February 7 (Wed.)

Sales : Re/U online store: https://online.reunet.jp/

*This product has a characteristic feel because it contains ingredients derived from natural sea sponges (skin conditioning ingredients).


<Notice of pre-sale

The product will be on sale from January 31 (Wed) to February 6 (Tue), 2024, at the "Re/U POPUP STORE" in East Park/Promotion on the 2nd floor of Isetan Shinjuku Main Building.



About the Re/U brand


Re/U" is an advanced biotechnology skincare brand.


Re/U" is a word coined from "Re" and "U" (you). Re/U" is a skincare brand that was launched with the intention of "restoring your skin to its original beauty. The supernatant fluid from stem cell culture is produced and managed in our own laboratory in Japan, and each ml contains 5 billion exosomes and more than 2,000 kinds of cytokines and other physiologically active substances, making it a "living cosmetic.

The Re/U skincare line offers "advanced beauty ingredients" that maintain beautiful skin, and can be used easily at home without the need to go to a specialized institution.



About BYINA Corporation

BYINA was established in February 2022 with the vision of "creating a healthy future with human stem cell culture supernatant" and owns its own laboratory in Japan. The company will develop a variety of products and services centered on cosmetics using highly concentrated stem cell culture supernatant solution purified in-house. We will continue to support people's health and beauty with stem cell culture supernatant solution, which was born from advanced biotechnology.


BYINA Corporation corporate website: https://byina.jp/

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